Spherocyte shape transformation and release of tubular nanovesicles in human erythrocytes.

نویسندگان

  • Ales Iglic
  • Peter Veranic
  • Kristijan Jezernik
  • Miha Fosnaric
  • Boris Kamin
  • Henry Hägerstrand
  • Veronika Kralj-Iglic
چکیده

We have studied dodecylmaltoside-induced echinocyte-spheroechincyte-spherocyte shape transformation and membrane vesiculation using transmission electron microscopy (TEM) on freeze-fracture replicas. It is indicated that spherical erythrocyte shape at higher dodecylmaltoside concentration is formed due to loss of membrane in the process where small, mostly tubular nanovesicles are released predominantly from the top of echinocyte and spheroechinocyte spicules.

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عنوان ژورنال:
  • Bioelectrochemistry

دوره 62 2  شماره 

صفحات  -

تاریخ انتشار 2004